Synthesis and evaluation of small libraries of triazolylmethoxy chalcones, flavanones and 2-aminopyrimidines as inhibitors of mycobacterial FAS-II and PknG. [electronic resource]
- Bioorganic & medicinal chemistry Sep 2012
- 5150-63 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3391
10.1016/j.bmc.2012.07.009 doi
Chalcones--chemical synthesis Dose-Response Relationship, Drug Enzyme Inhibitors--chemical synthesis Fatty Acid Synthase, Type II--antagonists & inhibitors Flavanones--chemical synthesis Molecular Structure Mycobacterium tuberculosis--enzymology Protein Serine-Threonine Kinases--antagonists & inhibitors Pyrimidines--chemical synthesis Small Molecule Libraries--chemical synthesis Structure-Activity Relationship Triazoles--chemical synthesis