TY  - GEN
AU  - Wanngren,Johanna
AU  - Ottervald,Jan
AU  - Parpal,Santiago
AU  - Portelius,Erik
AU  - Strömberg,Kia
AU  - Borgegård,Tomas
AU  - Klintenberg,Rebecka
AU  - Juréus,Anders
AU  - Blomqvist,Jenny
AU  - Blennow,Kaj
AU  - Zetterberg,Henrik
AU  - Lundkvist,Johan
AU  - Rosqvist,Susanne
AU  - Karlström,Helena
TI  - Second generation γ-secretase modulators exhibit different modulation of Notch β and Aβ production
SN  - 1083-351X
PY  - 2012///1207
KW  - Amyloid
KW  - genetics
KW  - Amyloid Precursor Protein Secretases
KW  - Amyloid beta-Protein Precursor
KW  - Animals
KW  - Anti-Inflammatory Agents, Non-Steroidal
KW  - pharmacology
KW  - Female
KW  - Flurbiprofen
KW  - HEK293 Cells
KW  - Humans
KW  - Mice
KW  - Protein Processing, Post-Translational
KW  - drug effects
KW  - Protein Structure, Tertiary
KW  - Receptors, Notch
KW  - Sulindac
KW  - analogs & derivatives
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1074/jbc.M112.376541
ER  -