Jiang, Li <br/><br/>
Combined effects of the ATP-sensitive potassium channel opener pinacidil and simvastatin on pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.  [electronic resource] 

 -  Die Pharmazie  Jun 2012 
 - 547-52 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0031-7144 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Actins--biosynthesis<br/>Animals<br/>Arterioles--pathology<br/>Blood Vessels--drug effects<br/>Cell Proliferation--drug effects<br/>Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology<br/>Hypertension, Pulmonary--chemically induced<br/>Immunochemistry<br/>Immunohistochemistry<br/>KATP Channels--agonists<br/>Male<br/>Matrix Metalloproteinase 2--biosynthesis<br/>Matrix Metalloproteinase 9--biosynthesis<br/>Monocrotaline<br/>Muscle, Smooth, Vascular--drug effects<br/>Myocytes, Smooth Muscle--drug effects<br/>Pinacidil--pharmacology<br/>Poisons<br/>Polymerase Chain Reaction<br/>Pulmonary Circulation--drug effects<br/>Rats<br/>Simvastatin--pharmacology<br/>Tissue Inhibitor of Metalloproteinase-1--metabolism<br/>Transforming Growth Factor beta--biosynthesis<br/>Vasodilator Agents--pharmacology