Mazhab-Jafari, Mohammad T <br/><br/>
An autoinhibited noncanonical mechanism of GTP hydrolysis by Rheb maintains mTORC1 homeostasis.  [electronic resource] 

 -  Structure (London, England : 1993)  Sep 2012 
 - 1528-39 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1878-4186 
<br/><br/><label>Standard No.: </label>10.1016/j.str.2012.06.013  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Motifs<br/>Amino Acid Substitution<br/>Animals<br/>Catalytic Domain<br/>Crystallography, X-Ray<br/>Enzyme Activation<br/>Guanosine Triphosphate--chemistry<br/>HEK293 Cells<br/>HeLa Cells<br/>Homeostasis<br/>Humans<br/>Hydrogen Bonding<br/>Hydrolysis<br/>Kinetics<br/>Mechanistic Target of Rapamycin Complex 1<br/>Mice<br/>Models, Molecular<br/>Monomeric GTP-Binding Proteins--chemistry<br/>Multiprotein Complexes<br/>Mutagenesis, Site-Directed<br/>Neuropeptides--chemistry<br/>Protein Binding<br/>Proteins--metabolism<br/>Ras Homolog Enriched in Brain Protein<br/>Ribosomal Protein S6 Kinases, 70-kDa--metabolism<br/>TOR Serine-Threonine Kinases<br/>Thermodynamics