Chen, Ming-Huang
Gene expression-based chemical genomics identifies heat-shock protein 90 inhibitors as potential therapeutic drugs in cholangiocarcinoma. [electronic resource]
- Cancer Jan 2013
- 293-303 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ISSN: 1097-0142
Standard No.: 10.1002/cncr.27743 doi
Subjects--Topical Terms: Animals Antineoplastic Agents--administration & dosage Apoptosis--drug effects Benzoquinones--administration & dosage Bile Duct Neoplasms--genetics Bile Ducts, Intrahepatic--metabolism Cell Line, Tumor Cell Survival--drug effects Cholangiocarcinoma--genetics Drug Evaluation, Preclinical Female G2 Phase Cell Cycle Checkpoints--drug effects Gene Expression Regulation, Neoplastic Genomics HSP90 Heat-Shock Proteins--antagonists & inhibitors Humans Inhibitory Concentration 50 Isoxazoles--administration & dosage Lactams, Macrocyclic--administration & dosage Liver Neoplasms, Experimental--chemically induced MAP Kinase Signaling System Male Middle Aged Oligonucleotide Array Sequence Analysis Rats Rats, Sprague-Dawley Resorcinols--administration & dosage Transcriptome Tumor Burden--drug effects