Chen, Ming-Huang

Gene expression-based chemical genomics identifies heat-shock protein 90 inhibitors as potential therapeutic drugs in cholangiocarcinoma. [electronic resource] - Cancer Jan 2013 - 293-303 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1097-0142

10.1002/cncr.27743 doi


Animals
Antineoplastic Agents--administration & dosage
Apoptosis--drug effects
Benzoquinones--administration & dosage
Bile Duct Neoplasms--genetics
Bile Ducts, Intrahepatic--metabolism
Cell Line, Tumor
Cell Survival--drug effects
Cholangiocarcinoma--genetics
Drug Evaluation, Preclinical
Female
G2 Phase Cell Cycle Checkpoints--drug effects
Gene Expression Regulation, Neoplastic
Genomics
HSP90 Heat-Shock Proteins--antagonists & inhibitors
Humans
Inhibitory Concentration 50
Isoxazoles--administration & dosage
Lactams, Macrocyclic--administration & dosage
Liver Neoplasms, Experimental--chemically induced
MAP Kinase Signaling System
Male
Middle Aged
Oligonucleotide Array Sequence Analysis
Rats
Rats, Sprague-Dawley
Resorcinols--administration & dosage
Transcriptome
Tumor Burden--drug effects