TY  - GEN
AU  - Simpson,Peter D
AU  - Moysi,Eirini
AU  - Wicks,Kate
AU  - Sudan,Kritika
AU  - Rowland-Jones,Sarah L
AU  - McMichael,Andrew J
AU  - Knight,Julian
AU  - Gillespie,Geraldine M
TI  - Functional differences exist between TNFα promoters encoding the common -237G SNP and the rarer HLA-B*5701-linked A variant
SN  - 1932-6203
PY  - 2013///0319
KW  - Animals
KW  - B-Lymphocytes
KW  - drug effects
KW  - Base Sequence
KW  - Cell Line
KW  - DNA Methylation
KW  - Epigenesis, Genetic
KW  - Genes, Reporter
KW  - HIV Infections
KW  - genetics
KW  - HLA-B Antigens
KW  - Haplotypes
KW  - Homozygote
KW  - Humans
KW  - Lipopolysaccharides
KW  - pharmacology
KW  - Luciferases
KW  - metabolism
KW  - Lymphocyte Activation
KW  - Mice
KW  - Molecular Sequence Data
KW  - Monocytes
KW  - cytology
KW  - Polymorphism, Single Nucleotide
KW  - Promoter Regions, Genetic
KW  - Protein Binding
KW  - RNA, Messenger
KW  - Software
KW  - Solubility
KW  - Tetradecanoylphorbol Acetate
KW  - Transcription Factors
KW  - Tumor Necrosis Factor-alpha
KW  - biosynthesis
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0040100
ER  -