Van der Jeught, Margot

The combination of inhibitors of FGF/MEK/Erk and GSK3β signaling increases the number of OCT3/4- and NANOG-positive cells in the human inner cell mass, but does not improve stem cell derivation. [electronic resource] - Stem cells and development Jan 2013 - 296-306 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1557-8534

10.1089/scd.2012.0256 doi


Benzamides--pharmacology
Blastocyst Inner Cell Mass--cytology
Cell Count
Cell Culture Techniques
Cell Lineage
Diphenylamine--analogs & derivatives
Embryo Culture Techniques
Embryo Implantation--drug effects
Embryonic Stem Cells--cytology
GATA6 Transcription Factor--genetics
Glycogen Synthase Kinase 3--antagonists & inhibitors
Glycogen Synthase Kinase 3 beta
Homeodomain Proteins--genetics
Humans
Immunohistochemistry
MAP Kinase Signaling System
Mitogen-Activated Protein Kinase Kinases--antagonists & inhibitors
Nanog Homeobox Protein
Octamer Transcription Factor-3--genetics
Pyridines--pharmacology
Pyrimidines--pharmacology
Signal Transduction
Time Factors