Zhang, Hongbo

Human UDP-glucuronosyltransferase expression in insect cells: ratio of active to inactive recombinant proteins and the effects of a C-terminal his-tag on glucuronidation kinetics. [electronic resource] - Drug metabolism and disposition: the biological fate of chemicals Oct 2012 - 1935-44 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-009X

10.1124/dmd.112.046086 doi


Animals
Baculoviridae--genetics
Blotting, Western
Catalytic Domain
Enzyme Activation
Glucuronides--metabolism
Glucuronosyltransferase--biosynthesis
Histidine--biosynthesis
Humans
Kinetics
Models, Biological
Mutation
Recombinant Fusion Proteins--metabolism
Sf9 Cells
Spodoptera
Substrate Specificity
Transfection
UDP-Glucuronosyltransferase 1A9