TY  - GEN
AU  - Qin,Zhihui
AU  - Luo,Jia
AU  - VandeVrede,Lawren
AU  - Tavassoli,Ehsan
AU  - Fa',Mauro
AU  - Teich,Andrew F
AU  - Arancio,Ottavio
AU  - Thatcher,Gregory R J
TI  - Design and synthesis of neuroprotective methylthiazoles and modification as NO-chimeras for neurodegenerative therapy
SN  - 1520-4804
PY  - 2012///1105
KW  - Alzheimer Disease
KW  - drug therapy
KW  - Amyloid beta-Protein Precursor
KW  - genetics
KW  - Animals
KW  - Avoidance Learning
KW  - drug effects
KW  - Biological Availability
KW  - Brain
KW  - metabolism
KW  - Click Chemistry
KW  - Cognition Disorders
KW  - Glucose
KW  - deficiency
KW  - Hippocampus
KW  - Humans
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Transgenic
KW  - Molecular Mimicry
KW  - Mutation
KW  - Neurons
KW  - cytology
KW  - Neuroprotective Agents
KW  - chemical synthesis
KW  - Nitric Oxide
KW  - chemistry
KW  - Oxygen
KW  - Primary Cell Culture
KW  - Prodrugs
KW  - Receptors, GABA-A
KW  - Small Molecule Libraries
KW  - Structure-Activity Relationship
KW  - Synaptic Transmission
KW  - Thiazoles
KW  - Tissue Distribution
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1021/jm300353r
ER  -