Cid, Jose Marķa <br/><br/>
Discovery of 1,5-disubstituted pyridones: a new class of positive allosteric modulators of the metabotropic glutamate 2 receptor.  [electronic resource] 

 -  ACS chemical neuroscience  Dec 2010 
 - 788-95 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1948-7193 
<br/><br/><label>Standard No.: </label>10.1021/cn1000638  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Allosteric Regulation<br/>Amino Acids--chemistry<br/>Animals<br/>Bridged Bicyclo Compounds--chemistry<br/>Drug Evaluation, Preclinical<br/>Drug Stability<br/>Excitatory Amino Acid Agonists--chemistry<br/>Humans<br/>Hydrophobic and Hydrophilic Interactions<br/>Mice<br/>Molecular Structure<br/>Motor Activity--drug effects<br/>Pyridines--chemistry<br/>Pyridones--chemistry<br/>Receptors, Metabotropic Glutamate--agonists<br/>Recombinant Proteins--drug effects<br/>Structure-Activity Relationship<br/>Sulfonamides--chemistry