TY  - GEN
AU  - Hu,Rong
AU  - Zhou,Ping
AU  - Peng,Yong-Bo
AU  - Xu,Xiaojun
AU  - Ma,Jiang
AU  - Liu,Qun
AU  - Zhang,Lei
AU  - Wen,Xiao-Dong
AU  - Qi,Lian-Wen
AU  - Gao,Ning
AU  - Li,Ping
TI  - 6-Shogaol induces apoptosis in human hepatocellular carcinoma cells and exhibits anti-tumor activity in vivo through endoplasmic reticulum stress
SN  - 1932-6203
PY  - 2012///1127
KW  - Animals
KW  - Antineoplastic Agents
KW  - administration & dosage
KW  - Apoptosis
KW  - drug effects
KW  - Carcinoma, Hepatocellular
KW  - enzymology
KW  - Catechols
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - Cinnamates
KW  - pharmacology
KW  - Dose-Response Relationship, Drug
KW  - Drug Screening Assays, Antitumor
KW  - Drug Synergism
KW  - Electrophoresis, Gel, Two-Dimensional
KW  - Endoplasmic Reticulum Stress
KW  - Eukaryotic Initiation Factor-2
KW  - metabolism
KW  - Humans
KW  - Liver Neoplasms
KW  - Mice
KW  - Neoplasm Proteins
KW  - Phosphorylation
KW  - RNA, Small Interfering
KW  - Thiourea
KW  - analogs & derivatives
KW  - Time Factors
KW  - Transcription Factor CHOP
KW  - Unfolded Protein Response
KW  - Up-Regulation
KW  - Xenograft Model Antitumor Assays
KW  - eIF-2 Kinase
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0039664
ER  -