Zhang, Shulin

Inhibition of CK2α down-regulates Hedgehog/Gli signaling leading to a reduction of a stem-like side population in human lung cancer cells. [electronic resource] - PloS one 2012 - e38996 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0038996 doi


ATP Binding Cassette Transporter, Subfamily G, Member 2
ATP-Binding Cassette Transporters--metabolism
Carcinoma, Non-Small-Cell Lung--genetics
Casein Kinase II--antagonists & inhibitors
Cell Count
Cell Line, Tumor
Down-Regulation--drug effects
Gene Expression Regulation, Neoplastic--drug effects
Gene Knockdown Techniques
Gene Silencing--drug effects
Humans
Lung Neoplasms--genetics
Neoplasm Proteins--metabolism
Neoplastic Stem Cells--drug effects
Protein Kinase Inhibitors--pharmacology
Proteolysis--drug effects
Side-Population Cells--drug effects
Signal Transduction--genetics
Small Molecule Libraries--pharmacology
Transcription Factors--genetics
Transcription, Genetic--drug effects
Transcriptional Activation--drug effects
Up-Regulation--drug effects
Zinc Finger Protein GLI1