Spurr, Ian B

Targeting tumour proliferation with a small-molecule inhibitor of AICAR transformylase homodimerization. [electronic resource] - Chembiochem : a European journal of chemical biology Jul 2012 - 1628-34 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1439-7633

10.1002/cbic.201200279 doi


Antineoplastic Agents--chemical synthesis
Breast Neoplasms--drug therapy
Catalytic Domain--drug effects
Cell Count
Cell Division--drug effects
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Enzyme Inhibitors--chemical synthesis
Female
High-Throughput Screening Assays
Humans
MCF-7 Cells
Molecular Structure
Molecular Weight
Peptides, Cyclic--chemical synthesis
Phosphoribosylaminoimidazolecarboxamide Formyltransferase--antagonists & inhibitors
Protein Multimerization--drug effects
Structure-Activity Relationship