TY  - GEN
AU  - Mendler,Jason H
AU  - Maharry,Kati
AU  - Radmacher,Michael D
AU  - Mrózek,Krzysztof
AU  - Becker,Heiko
AU  - Metzeler,Klaus H
AU  - Schwind,Sebastian
AU  - Whitman,Susan P
AU  - Khalife,Jihane
AU  - Kohlschmidt,Jessica
AU  - Nicolet,Deedra
AU  - Powell,Bayard L
AU  - Carter,Thomas H
AU  - Wetzler,Meir
AU  - Moore,Joseph O
AU  - Kolitz,Jonathan E
AU  - Baer,Maria R
AU  - Carroll,Andrew J
AU  - Larson,Richard A
AU  - Caligiuri,Michael A
AU  - Marcucci,Guido
AU  - Bloomfield,Clara D
TI  - RUNX1 mutations are associated with poor outcome in younger and older patients with cytogenetically normal acute myeloid leukemia and with distinct gene and MicroRNA expression signatures
SN  - 1527-7755
PY  - 2012///1107
KW  - Adolescent
KW  - Adult
KW  - Age Factors
KW  - Aged
KW  - Aged, 80 and over
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - therapeutic use
KW  - Core Binding Factor Alpha 2 Subunit
KW  - genetics
KW  - Cytogenetic Analysis
KW  - DNA Mutational Analysis
KW  - Disease Progression
KW  - Disease-Free Survival
KW  - Female
KW  - Gene Expression Profiling
KW  - methods
KW  - Gene Expression Regulation, Neoplastic
KW  - Genetic Predisposition to Disease
KW  - Humans
KW  - Kaplan-Meier Estimate
KW  - Leukemia, Myeloid, Acute
KW  - drug therapy
KW  - Logistic Models
KW  - Male
KW  - MicroRNAs
KW  - metabolism
KW  - Middle Aged
KW  - Multivariate Analysis
KW  - Mutation
KW  - Nucleophosmin
KW  - Oligonucleotide Array Sequence Analysis
KW  - Phenotype
KW  - Polymerase Chain Reaction
KW  - Proportional Hazards Models
KW  - Risk Assessment
KW  - Risk Factors
KW  - Time Factors
KW  - Treatment Outcome
KW  - United States
KW  - Young Adult
N1  - Publication Type: Clinical Trial; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1200/JCO.2011.40.6652
ER  -