Mendler, Jason H <br/><br/>
RUNX1 mutations are associated with poor outcome in younger and older patients with cytogenetically normal acute myeloid leukemia and with distinct gene and MicroRNA expression signatures.  [electronic resource] 

 -  Journal of clinical oncology : official journal of the American Society of Clinical Oncology  Sep 2012 
 - 3109-18 p.  digital 
<br/><br/> Publication Type: Clinical Trial; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1527-7755 
<br/><br/><label>Standard No.: </label>10.1200/JCO.2011.40.6652  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adolescent<br/>Adult<br/>Age Factors<br/>Aged<br/>Aged, 80 and over<br/>Antineoplastic Combined Chemotherapy Protocols--therapeutic use<br/>Core Binding Factor Alpha 2 Subunit--genetics<br/>Cytogenetic Analysis<br/>DNA Mutational Analysis<br/>Disease Progression<br/>Disease-Free Survival<br/>Female<br/>Gene Expression Profiling--methods<br/>Gene Expression Regulation, Neoplastic<br/>Genetic Predisposition to Disease<br/>Humans<br/>Kaplan-Meier Estimate<br/>Leukemia, Myeloid, Acute--drug therapy<br/>Logistic Models<br/>Male<br/>MicroRNAs--metabolism<br/>Middle Aged<br/>Multivariate Analysis<br/>Mutation<br/>Nucleophosmin<br/>Oligonucleotide Array Sequence Analysis<br/>Phenotype<br/>Polymerase Chain Reaction<br/>Proportional Hazards Models<br/>Risk Assessment<br/>Risk Factors<br/>Time Factors<br/>Treatment Outcome<br/>United States<br/>Young Adult