Wennerstrand, Patricia

Structural characteristics determine the cause of the low enzyme activity of two thiopurine S-methyltransferase allelic variants: a biophysical characterization of TPMT*2 and TPMT*5. [electronic resource] - Biochemistry Jul 2012 - 5912-20 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4995

10.1021/bi300377d doi


Alleles
Amino Acid Sequence
Catalytic Domain--genetics
Enzyme Activation--genetics
Genetic Variation--genetics
Humans
Methyltransferases--chemistry
Molecular Sequence Data