TY - GEN AU - Zhang,Jingwei AU - Lu,Meng AU - Zhou,Fang AU - Sun,Haopeng AU - Hao,Gang AU - Wu,Xiaolan AU - Wang,Guangji TI - Key role of nuclear factor-κB in the cellular pharmacokinetics of adriamycin in MCF-7/Adr cells: the potential mechanism for synergy with 20(S)-ginsenoside Rh2 SN - 1521-009X PY - 2013///0214 KW - ATP Binding Cassette Transporter, Subfamily B KW - ATP Binding Cassette Transporter, Subfamily B, Member 1 KW - antagonists & inhibitors KW - Active Transport, Cell Nucleus KW - Antibiotics, Antineoplastic KW - metabolism KW - Antineoplastic Combined Chemotherapy Protocols KW - pharmacokinetics KW - Binding Sites KW - Breast Neoplasms KW - genetics KW - Doxorubicin KW - Drug Resistance, Neoplasm KW - drug effects KW - Drug Synergism KW - Enzyme Activation KW - Female KW - Gene Expression Regulation, Neoplastic KW - Ginsenosides KW - pharmacology KW - Humans KW - I-kappa B Kinase KW - MCF-7 Cells KW - Mitogen-Activated Protein Kinases KW - NF-kappa B KW - Phosphorylation KW - Promoter Regions, Genetic KW - RNA Interference KW - Signal Transduction KW - Transcription Factor RelA KW - Transfection N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1124/dmd.112.045187 ER -