TY - GEN AU - Smith,Aaron T AU - Su,Yang AU - Stevens,Daniel J AU - Majtan,Tomas AU - Kraus,Jan P AU - Burstyn,Judith N TI - Effect of the disease-causing R266K mutation on the heme and PLP environments of human cystathionine β-synthase SN - 1520-4995 PY - 2012///1029 KW - Catalytic Domain KW - Circular Dichroism KW - Cystathionine beta-Synthase KW - chemistry KW - Electron Spin Resonance Spectroscopy KW - Enzyme Stability KW - Ferrous Compounds KW - Heme KW - genetics KW - Homocystinuria KW - Humans KW - Models, Molecular KW - Mutation KW - Oxidation-Reduction KW - Protein Binding KW - Pyridoxal Phosphate KW - Spectrometry, Fluorescence KW - Spectrum Analysis, Raman KW - Temperature N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/bi300421z ER -