Long-term proteasomal inhibition in transgenic mice by UBB(+1) expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients. [electronic resource]
- Acta neuropathologica Aug 2012
- 187-97 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1432-0533
10.1007/s00401-012-1003-7 doi
Aged Aged, 80 and over Alzheimer Disease--genetics Animals Brain Stem--metabolism Disease Models, Animal Female Humans Male Mice Mice, Transgenic Middle Aged Neurons--metabolism Phenotype Proteasome Endopeptidase Complex--genetics Respiration Ubiquitin--genetics