TY - GEN AU - Stayner,Cherie AU - Shields,Justin AU - Slobbe,Lynn AU - Shillingford,Jonathan M AU - Weimbs,Thomas AU - Eccles,Michael R TI - Rapamycin-mediated suppression of renal cyst expansion in del34 Pkd1-/- mutant mouse embryos: an investigation of the feasibility of renal cyst prevention in the foetus SN - 1440-1797 PY - 2013///0422 KW - Animals KW - Embryo, Mammalian KW - drug effects KW - Feasibility Studies KW - Female KW - Gene Expression Regulation, Developmental KW - Genetic Predisposition to Disease KW - Gestational Age KW - Homozygote KW - Kidney KW - Male KW - Mice KW - Mice, Inbred C3H KW - Mice, Knockout KW - PAX2 Transcription Factor KW - metabolism KW - Phenotype KW - Polycystic Kidney, Autosomal Dominant KW - embryology KW - Protein Kinase Inhibitors KW - pharmacology KW - Sequence Deletion KW - Signal Transduction KW - Sirolimus KW - TOR Serine-Threonine Kinases KW - antagonists & inhibitors KW - TRPP Cation Channels KW - deficiency N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1111/j.1440-1797.2012.01639.x ER -