TY - GEN AU - Balmer,Nina V AU - Weng,Matthias K AU - Zimmer,Bastian AU - Ivanova,Violeta N AU - Chambers,Stuart M AU - Nikolaeva,Elena AU - Jagtap,Smita AU - Sachinidis,Agapios AU - Hescheler,Jürgen AU - Waldmann,Tanja AU - Leist,Marcel TI - Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome SN - 1460-2083 PY - 2013///0117 KW - Abnormalities, Drug-Induced KW - genetics KW - Antigens, Differentiation KW - Basic Helix-Loop-Helix Transcription Factors KW - Cell Differentiation KW - drug effects KW - Cells, Cultured KW - Embryonic Stem Cells KW - metabolism KW - Epigenesis, Genetic KW - Eye Proteins KW - Histone Deacetylase Inhibitors KW - pharmacology KW - Histones KW - Homeodomain Proteins KW - Humans KW - Hydroxamic Acids KW - Methylation KW - Nanog Homeobox Protein KW - Neural Plate KW - embryology KW - Neural Stem Cells KW - Neuroepithelial Cells KW - Octamer Transcription Factor-3 KW - Oligonucleotide Array Sequence Analysis KW - PAX6 Transcription Factor KW - Paired Box Transcription Factors KW - Principal Component Analysis KW - Promoter Regions, Genetic KW - Protein Processing, Post-Translational KW - Repressor Proteins KW - Transcription, Genetic KW - Transcriptome KW - Valproic Acid KW - adverse effects N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/hmg/dds239 ER -