Site-specific PEGylation of therapeutic proteins via optimization of both accessible reactive amino acid residues and PEG derivatives. [electronic resource]
- BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy Aug 2012
- 209-15 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review
1179-190X
10.1007/BF03261880 doi
Amino Acids--chemistry Binding Sites Drug Carriers--chemistry Molecular Structure Mutagenesis, Site-Directed Polyethylene Glycols--chemistry Protein Engineering--methods Proteins--administration & dosage Sulfhydryl Compounds--chemistry