TY - GEN AU - Ema,Tadashi AU - Nakano,Yasuko AU - Yoshida,Daiki AU - Kamata,Shusuke AU - Sakai,Takashi TI - Redesign of enzyme for improving catalytic activity and enantioselectivity toward poor substrates: manipulation of the transition state SN - 1477-0539 PY - 2012///1126 KW - Burkholderia cepacia KW - enzymology KW - Kinetics KW - Lipase KW - genetics KW - Models, Molecular KW - Mutation KW - Stereoisomerism KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1039/c2ob25614b ER -