TY - GEN AU - Isoda,Takeshi AU - Takagi,Masatoshi AU - Piao,Jinhua AU - Nakagama,Shun AU - Sato,Masaki AU - Masuda,Kyoko AU - Ikawa,Tomokatsu AU - Azuma,Miyuki AU - Morio,Tomohiro AU - Kawamoto,Hiroshi AU - Mizutani,Shuki TI - Process for immune defect and chromosomal translocation during early thymocyte development lacking ATM SN - 1528-0020 PY - 2012///1009 KW - Animals KW - Apoptosis KW - Ataxia Telangiectasia Mutated Proteins KW - Blotting, Western KW - Bone Marrow Transplantation KW - CD4-Positive T-Lymphocytes KW - immunology KW - CD8-Positive T-Lymphocytes KW - Cell Cycle KW - Cell Cycle Proteins KW - physiology KW - Cell Differentiation KW - Cell Proliferation KW - DNA-Binding Proteins KW - Female KW - Flow Cytometry KW - Gene Rearrangement, T-Lymphocyte KW - Genomic Instability KW - In Situ Hybridization, Fluorescence KW - Karyotyping KW - Male KW - Mice KW - Mice, Inbred BALB C KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Protein Serine-Threonine Kinases KW - RNA, Messenger KW - genetics KW - Real-Time Polymerase Chain Reaction KW - Receptors, Antigen, T-Cell, alpha-beta KW - metabolism KW - Reverse Transcriptase Polymerase Chain Reaction KW - Thymocytes KW - Translocation, Genetic KW - Tumor Suppressor Proteins KW - V(D)J Recombination N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1182/blood-2012-02-413195 ER -