ERK1/2, p38, and JNK regulate the expression and the activity of the three isoforms of the Na+ /Ca2+ exchanger, NCX1, NCX2, and NCX3, in neuronal PC12 cells. [electronic resource]
- Journal of neurochemistry Sep 2012
- 911-22 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1471-4159
10.1111/j.1471-4159.2012.07838.x doi
Animals CREB-Binding Protein--genetics Calcium--metabolism Cell Differentiation--drug effects Chromatin Immunoprecipitation Cyclic AMP--pharmacology Dose-Response Relationship, Drug Enzyme Inhibitors--pharmacology Gene Expression Regulation, Enzymologic--drug effects MAP Kinase Kinase 4 MAP Kinase Signaling System--drug effects Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinases--metabolism Nerve Growth Factor--pharmacology Nerve Tissue Proteins--metabolism Neurons--drug effects PC12 Cells--drug effects Protein Isoforms--genetics RNA, Small Interfering--pharmacology Rats Sodium-Calcium Exchanger--classification Sp1 Transcription Factor--metabolism Time Factors p38 Mitogen-Activated Protein Kinases