TY - GEN AU - Scicinski,Jan AU - Oronsky,Bryan AU - Taylor,Michael AU - Luo,Gang AU - Musick,Timothy AU - Marini,Joseph AU - Adams,Christopher M AU - Fitch,William L TI - Preclinical evaluation of the metabolism and disposition of RRx-001, a novel investigative anticancer agent SN - 1521-009X PY - 2013///0117 KW - Alkylation KW - Animals KW - Antineoplastic Agents KW - administration & dosage KW - Azetidines KW - Biotransformation KW - Chromatography, Liquid KW - Cysteine KW - Dogs KW - Erythrocytes KW - metabolism KW - Haplorhini KW - Hemoglobins KW - Humans KW - Injections, Intravenous KW - Kidney KW - Male KW - Metabolic Clearance Rate KW - Nitro Compounds KW - Peptide Mapping KW - Protein Binding KW - Proteomics KW - methods KW - Rats KW - Rats, Wistar KW - Sulfhydryl Compounds KW - Tandem Mass Spectrometry KW - Tissue Distribution KW - beta-Globins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1124/dmd.112.046755 ER -