TY - GEN AU - Daoussis,Dimitrios AU - Tsamandas,Athanassios C AU - Liossis,Stamatis-Nick C AU - Antonopoulos,Ioannis AU - Karatza,Elli AU - Yiannopoulos,Georgios AU - Andonopoulos,Andrew P TI - B-cell depletion therapy in patients with diffuse systemic sclerosis associates with a significant decrease in PDGFR expression and activation in spindle-like cells in the skin SN - 1478-6362 PY - 2013///0522 KW - Adult KW - Antibodies, Monoclonal, Murine-Derived KW - therapeutic use KW - Antirheumatic Agents KW - B-Lymphocytes KW - drug effects KW - Female KW - Fibrosis KW - Humans KW - Immunohistochemistry KW - Lymphocyte Depletion KW - methods KW - Male KW - Middle Aged KW - Receptor, Platelet-Derived Growth Factor alpha KW - biosynthesis KW - Receptor, Platelet-Derived Growth Factor beta KW - Receptors, Platelet-Derived Growth Factor KW - metabolism KW - Rituximab KW - Scleroderma, Diffuse KW - drug therapy KW - Skin N1 - Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1186/ar3879 ER -