Daoussis, Dimitrios

B-cell depletion therapy in patients with diffuse systemic sclerosis associates with a significant decrease in PDGFR expression and activation in spindle-like cells in the skin. [electronic resource] - Arthritis research & therapy Jun 2012 - R145 p. digital

Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

1478-6362

10.1186/ar3879 doi


Adult
Antibodies, Monoclonal, Murine-Derived--therapeutic use
Antirheumatic Agents--therapeutic use
B-Lymphocytes--drug effects
Female
Fibrosis
Humans
Immunohistochemistry
Lymphocyte Depletion--methods
Male
Middle Aged
Receptor, Platelet-Derived Growth Factor alpha--biosynthesis
Receptor, Platelet-Derived Growth Factor beta--biosynthesis
Receptors, Platelet-Derived Growth Factor--metabolism
Rituximab
Scleroderma, Diffuse--drug therapy
Skin--metabolism