TY - GEN AU - Rani,Mridula AU - Bolles,Meagan AU - Donaldson,Eric F AU - Van Blarcom,Thomas AU - Baric,Ralph AU - Iverson,Brent AU - Georgiou,George TI - Increased antibody affinity confers broad in vitro protection against escape mutants of severe acute respiratory syndrome coronavirus SN - 1098-5514 PY - 2012///1105 KW - Amino Acid Sequence KW - Animals KW - Antibodies, Neutralizing KW - chemistry KW - Antibodies, Viral KW - Antibody Affinity KW - Cell Line KW - Humans KW - Kinetics KW - Molecular Sequence Data KW - Mutation KW - Neutralization Tests KW - Severe acute respiratory syndrome-related coronavirus KW - Sequence Alignment KW - Severe Acute Respiratory Syndrome KW - immunology KW - Single-Chain Antibodies KW - genetics N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1128/JVI.00233-12 ER -