Goineau, Sonia <br/><br/>
The comparative sensitivity of three in vitro safety pharmacology models for the detection of lidocaine-induced cardiac effects.  [electronic resource] 

 -  Journal of pharmacological and toxicological methods  Jul 2012 
 - 52-8 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article 
<br/><br/><label>ISSN: </label>1873-488X 
<br/><br/><label>Standard No.: </label>10.1016/j.vascn.2012.06.001  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Action Potentials--drug effects<br/>Animals<br/>Atrial Function<br/>Dose-Response Relationship, Drug<br/>Drug Evaluation, Preclinical<br/>Guinea Pigs<br/>HEK293 Cells<br/>Heart--drug effects<br/>Heart Atria--drug effects<br/>Humans<br/>Lidocaine--toxicity<br/>Male<br/>Patch-Clamp Techniques--methods<br/>Purkinje Fibers--drug effects<br/>Rabbits<br/>Sensitivity and Specificity<br/>Toxicity Tests<br/>Transfection<br/>Voltage-Gated Sodium Channel Blockers--toxicity