TY  - GEN
AU  - Garrido-Laguna,Ignacio
AU  - Hong,David S
AU  - Janku,Filip
AU  - Nguyen,Ly M
AU  - Falchook,Gerald S
AU  - Fu,Siqing
AU  - Wheler,Jenifer J
AU  - Luthra,Rajyalakshmi
AU  - Naing,Aung
AU  - Wang,Xuemei
AU  - Kurzrock,Razelle
TI  - KRASness and PIK3CAness in patients with advanced colorectal cancer: outcome after treatment with early-phase trials with targeted pathway inhibitors
SN  - 1932-6203
PY  - 2012///0917
KW  - Adult
KW  - Aged
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Class I Phosphatidylinositol 3-Kinases
KW  - Colorectal Neoplasms
KW  - drug therapy
KW  - Female
KW  - Humans
KW  - MAP Kinase Signaling System
KW  - drug effects
KW  - Male
KW  - Middle Aged
KW  - Mutation
KW  - Mutation Rate
KW  - Neoplasm Metastasis
KW  - Phosphatidylinositol 3-Kinases
KW  - genetics
KW  - Protein Kinase Inhibitors
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins c-akt
KW  - metabolism
KW  - Proto-Oncogene Proteins p21(ras)
KW  - Signal Transduction
KW  - TOR Serine-Threonine Kinases
KW  - Treatment Outcome
KW  - ras Proteins
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1371/journal.pone.0038033
ER  -