TY - GEN AU - Kurzrock,Razelle AU - Goel,Sanjay AU - Wheler,Jennifer AU - Hong,David AU - Fu,Siqing AU - Rezai,Keyvan AU - Morgan-Linnell,Sonia K AU - Urien,Saik AU - Mani,Sridhar AU - Chaudhary,Imran AU - Ghalib,Mohammed H AU - Buchbinder,Aby AU - Lokiec,François AU - Mulcahy,Mary TI - Safety, pharmacokinetics, and activity of EZN-2208, a novel conjugate of polyethylene glycol and SN38, in patients with advanced malignancies SN - 1097-0142 PY - 2013///0205 KW - Adult KW - Aged KW - Camptothecin KW - analogs & derivatives KW - DNA, Neoplasm KW - genetics KW - Female KW - Follow-Up Studies KW - Glucuronosyltransferase KW - blood KW - Humans KW - Male KW - Maximum Tolerated Dose KW - Middle Aged KW - Neoplasm Staging KW - Neoplasms KW - drug therapy KW - Polyethylene Glycols KW - pharmacokinetics KW - Polymerase Chain Reaction KW - Polymorphism, Genetic KW - Prognosis KW - Safety KW - Tissue Distribution N1 - Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/cncr.27647 ER -