TY  - GEN
AU  - Chien,Chin-Hsiang
AU  - Gao,Quan-Ze
AU  - Cooper,Arthur J L
AU  - Lyu,Jyun-Hong
AU  - Sheu,Sheh-Yi
TI  - Structural insights into the catalytic active site and activity of human Nit2/ω-amidase: kinetic assay and molecular dynamics simulation
SN  - 1083-351X
PY  - 2012///1011
KW  - Amino Acid Sequence
KW  - Amino Acid Substitution
KW  - Aminohydrolases
KW  - biosynthesis
KW  - Animals
KW  - Asparagine
KW  - analogs & derivatives
KW  - Catalytic Domain
KW  - Conserved Sequence
KW  - Humans
KW  - Hydrolysis
KW  - Ketoglutaric Acids
KW  - chemistry
KW  - Kinetics
KW  - Mice
KW  - Molecular Dynamics Simulation
KW  - Molecular Sequence Data
KW  - Mutagenesis, Site-Directed
KW  - Protein Binding
KW  - Protein Structure, Quaternary
KW  - Protein Structure, Secondary
KW  - Recombinant Proteins
KW  - Sequence Deletion
KW  - Structural Homology, Protein
KW  - Substrate Specificity
KW  - Surface Properties
KW  - Thermodynamics
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.M111.259119
ER  -