TY - GEN AU - Yang,Dejun AU - Li,Tianxia AU - Liu,Zhaohui AU - Arbez,Nicolas AU - Yan,Jianqun AU - Moran,Timothy H AU - Ross,Christopher A AU - Smith,Wanli W TI - LRRK2 kinase activity mediates toxic interactions between genetic mutation and oxidative stress in a Drosophila model: suppression by curcumin SN - 1095-953X PY - 2012///1129 KW - Analysis of Variance KW - Animals KW - Animals, Genetically Modified KW - Cell Survival KW - drug effects KW - Cerebral Cortex KW - cytology KW - Curcumin KW - pharmacology KW - Dopamine KW - metabolism KW - Drosophila KW - Drosophila Proteins KW - genetics KW - Drug Interactions KW - Enzyme Inhibitors KW - Gene Expression Regulation KW - Green Fluorescent Proteins KW - Humans KW - Hydrogen Peroxide KW - Immunoprecipitation KW - Indoles KW - Mice KW - Models, Animal KW - Motor Activity KW - Mutation KW - Neurons KW - Oxidants KW - Oxidation-Reduction KW - Phenols KW - Phosphorylation KW - Protein Serine-Threonine Kinases KW - Survival Analysis KW - Transfection N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.nbd.2012.05.020 ER -