Ménochet, Karelle <br/><br/>
Use of mechanistic modeling to assess interindividual variability and interspecies differences in active uptake in human and rat hepatocytes.  [electronic resource] 

 -  Drug metabolism and disposition: the biological fate of chemicals  Sep 2012 
 - 1744-56 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1521-009X 
<br/><br/><label>Standard No.: </label>10.1124/dmd.112.046193  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Angiotensin II Type 1 Receptor Blockers--metabolism<br/>Animals<br/>Antihypertensive Agents--metabolism<br/>Benzimidazoles--metabolism<br/>Benzoates--metabolism<br/>Biological Transport<br/>Bosentan<br/>Carbamates--metabolism<br/>Dose-Response Relationship, Drug<br/>Drug Interactions<br/>Fluorobenzenes--metabolism<br/>Hepatocytes--drug effects<br/>Humans<br/>Hydroxymethylglutaryl-CoA Reductase Inhibitors--metabolism<br/>Hypoglycemic Agents--metabolism<br/>Kinetics<br/>Models, Biological<br/>Organic Anion Transporters--drug effects<br/>Piperidines--metabolism<br/>Pravastatin--metabolism<br/>Pyrimidines--metabolism<br/>Quinolines--metabolism<br/>Rats<br/>Rosuvastatin Calcium<br/>Species Specificity<br/>Sulfonamides--metabolism<br/>Telmisartan<br/>Tetrazoles--metabolism<br/>Valine--analogs & derivatives<br/>Valsartan