TY - GEN AU - Desch,Anna AU - Strozyk,Elwira A AU - Bauer,Alexander T AU - Huck,Volker AU - Niemeyer,Verena AU - Wieland,Thomas AU - Schneider,Stefan W TI - Highly invasive melanoma cells activate the vascular endothelium via an MMP-2/integrin αvβ5-induced secretion of VEGF-A SN - 1525-2191 PY - 2012///1126 KW - Adult KW - Animals KW - Cell Line, Tumor KW - Cell Membrane KW - metabolism KW - Endothelium, Vascular KW - enzymology KW - Enzyme Activation KW - Gene Expression Regulation, Neoplastic KW - Gene Knockdown Techniques KW - Humans KW - Male KW - Matrix Metalloproteinase 14 KW - Matrix Metalloproteinase 2 KW - Melanoma KW - blood supply KW - Mice KW - Models, Biological KW - Neoplasm Invasiveness KW - Neovascularization, Pathologic KW - genetics KW - Phosphatidylinositol 3-Kinases KW - RNA, Messenger KW - Receptors, Vitronectin KW - Signal Transduction KW - Skin Neoplasms KW - Vascular Endothelial Growth Factor A KW - Vascular Endothelial Growth Factor Receptor-2 KW - von Willebrand Factor N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.ajpath.2012.04.012 ER -