Desch, Anna <br/><br/>
Highly invasive melanoma cells activate the vascular endothelium via an MMP-2/integrin αvβ5-induced secretion of VEGF-A.  [electronic resource] 

 -  The American journal of pathology  Aug 2012 
 - 693-705 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1525-2191 
<br/><br/><label>Standard No.: </label>10.1016/j.ajpath.2012.04.012  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Animals<br/>Cell Line, Tumor<br/>Cell Membrane--metabolism<br/>Endothelium, Vascular--enzymology<br/>Enzyme Activation<br/>Gene Expression Regulation, Neoplastic<br/>Gene Knockdown Techniques<br/>Humans<br/>Male<br/>Matrix Metalloproteinase 14--metabolism<br/>Matrix Metalloproteinase 2--metabolism<br/>Melanoma--blood supply<br/>Mice<br/>Models, Biological<br/>Neoplasm Invasiveness<br/>Neovascularization, Pathologic--genetics<br/>Phosphatidylinositol 3-Kinases--metabolism<br/>RNA, Messenger--genetics<br/>Receptors, Vitronectin--metabolism<br/>Signal Transduction<br/>Skin Neoplasms--blood supply<br/>Vascular Endothelial Growth Factor A--genetics<br/>Vascular Endothelial Growth Factor Receptor-2--metabolism<br/>von Willebrand Factor--metabolism