Mattos, Adriana <br/><br/>
PEGylation of interleukin-10 improves the pharmacokinetic profile and enhances the antifibrotic effectivity in CCl₄-induced fibrogenesis in mice.  [electronic resource] 

 -  Journal of controlled release : official journal of the Controlled Release Society  Aug 2012 
 - 84-91 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1873-4995 
<br/><br/><label>Standard No.: </label>10.1016/j.jconrel.2012.05.041  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Carbon Tetrachloride<br/>Cell Line<br/>Collagen--metabolism<br/>Half-Life<br/>Humans<br/>Interleukin-10--chemistry<br/>Interleukin-1beta--genetics<br/>Interleukin-6--genetics<br/>Liver--drug effects<br/>Liver Cirrhosis--chemically induced<br/>Macrophages--drug effects<br/>Male<br/>Mice<br/>Mice, Inbred C57BL<br/>Polyethylene Glycols--chemistry<br/>Transcriptional Activation--drug effects<br/>Tumor Necrosis Factor-alpha--immunology