Yuan, Qianying

A new protoapigenone analog RY10-4 induces apoptosis and suppresses invasion through the PI3K/Akt pathway in human breast cancer. [electronic resource] - Cancer letters Nov 2012 - 210-20 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1872-7980

10.1016/j.canlet.2012.05.025 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Blotting, Western
Breast Neoplasms--drug therapy
Cell Line, Tumor
Cell Movement--drug effects
Cell Proliferation--drug effects
Cell Survival--drug effects
Dose-Response Relationship, Drug
Female
Humans
Mice
Mice, Inbred BALB C
Mice, Nude
Neoplasm Invasiveness
Phosphatidylinositol 3-Kinase--metabolism
Proto-Oncogene Proteins c-akt--metabolism
Pyrones--pharmacology
S Phase Cell Cycle Checkpoints--drug effects
Signal Transduction--drug effects
Time Factors
Tumor Burden--drug effects
Xenograft Model Antitumor Assays