TY - GEN AU - Chen,Xu-Zheng AU - Cao,Zhi-Yun AU - Chen,Tuan-Sheng AU - Zhang,You-Quan AU - Liu,Zhi-Zhen AU - Su,Yin-Tao AU - Liao,Lian-Ming AU - Du,Jian TI - Water extract of Hedyotis Diffusa Willd suppresses proliferation of human HepG2 cells and potentiates the anticancer efficacy of low-dose 5-fluorouracil by inhibiting the CDK2-E2F1 pathway SN - 1791-2431 PY - 2013///0124 KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - pharmacology KW - Carcinoma, Hepatocellular KW - drug therapy KW - Cell Growth Processes KW - drug effects KW - Cell Line, Tumor KW - Cyclin-Dependent Kinase 2 KW - antagonists & inhibitors KW - Dose-Response Relationship, Drug KW - Drug Synergism KW - E2F1 Transcription Factor KW - Female KW - Fluorouracil KW - administration & dosage KW - G1 Phase Cell Cycle Checkpoints KW - Hedyotis KW - chemistry KW - Hep G2 Cells KW - Humans KW - Liver Neoplasms KW - Mice KW - Mice, Inbred BALB C KW - Mice, Nude KW - Plant Extracts KW - RNA, Messenger KW - biosynthesis KW - Resting Phase, Cell Cycle KW - S Phase KW - Water KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.3892/or.2012.1834 ER -