Chen, Xu-Zheng <br/><br/>
Water extract of Hedyotis Diffusa Willd suppresses proliferation of             human HepG2 cells and potentiates the anticancer efficacy of low-dose 5-fluorouracil             by inhibiting the CDK2-E2F1 pathway.  [electronic resource] 

 -  Oncology reports  Aug 2012 
 - 742-8 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1791-2431 
<br/><br/><label>Standard No.: </label>10.3892/or.2012.1834  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Combined Chemotherapy Protocols--pharmacology<br/>Carcinoma, Hepatocellular--drug therapy<br/>Cell Growth Processes--drug effects<br/>Cell Line, Tumor<br/>Cyclin-Dependent Kinase 2--antagonists & inhibitors<br/>Dose-Response Relationship, Drug<br/>Drug Synergism<br/>E2F1 Transcription Factor--antagonists & inhibitors<br/>Female<br/>Fluorouracil--administration & dosage<br/>G1 Phase Cell Cycle Checkpoints--drug effects<br/>Hedyotis--chemistry<br/>Hep G2 Cells<br/>Humans<br/>Liver Neoplasms--drug therapy<br/>Mice<br/>Mice, Inbred BALB C<br/>Mice, Nude<br/>Plant Extracts--administration & dosage<br/>RNA, Messenger--biosynthesis<br/>Resting Phase, Cell Cycle--drug effects<br/>S Phase--drug effects<br/>Water--chemistry<br/>Xenograft Model Antitumor Assays