TY - GEN AU - Guo,Yan AU - Tang,Jiali AU - Du,Lei AU - Liu,Jin AU - Liu,Raphael C AU - Liu,Xiang AU - Guo,Yingqiang TI - Protamine dosage based on two titrations reduces blood loss after valve replacement surgery: a prospective, double-blinded, randomized study SN - 1916-7075 PY - 2012///1207 KW - Adult KW - Cardiopulmonary Bypass KW - adverse effects KW - Chi-Square Distribution KW - Dose-Response Relationship, Drug KW - Double-Blind Method KW - Drug Administration Schedule KW - Female KW - Follow-Up Studies KW - Heart Valve Prosthesis Implantation KW - Heparin KW - administration & dosage KW - Heparin Antagonists KW - Humans KW - Male KW - Middle Aged KW - Postoperative Hemorrhage KW - drug therapy KW - Prospective Studies KW - Protamines KW - Reference Values KW - Risk Assessment KW - Treatment Outcome N1 - Publication Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.cjca.2012.03.012 ER -