Kim, Sangmin

A functional comparison between the HER2(high)/HER3 and the HER2(low)/HER3 dimers on heregulin-β1-induced MMP-1 and MMP-9 expression in breast cancer cells. [electronic resource] - Experimental & molecular medicine Aug 2012 - 473-82 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2092-6413

10.3858/emm.2012.44.8.054 doi


Breast Neoplasms--enzymology
Butadienes--pharmacology
Cell Line, Tumor
Dose-Response Relationship, Drug
Enzyme Inhibitors--pharmacology
Female
Gene Expression
Gene Expression Regulation, Neoplastic--drug effects
Humans
Lapatinib
MAP Kinase Signaling System
MCF-7 Cells
Matrix Metalloproteinase 1--genetics
Matrix Metalloproteinase 9--genetics
Neuregulin-1--pharmacology
Nitriles--pharmacology
Phosphatidylinositol 3-Kinases--metabolism
Protein Kinase Inhibitors--pharmacology
Protein Multimerization
Proto-Oncogene Proteins c-akt--metabolism
Quinazolines--pharmacology
Receptor, ErbB-2--genetics
Receptor, ErbB-3--metabolism