Barten, Donna M

Hyperdynamic microtubules, cognitive deficits, and pathology are improved in tau transgenic mice with low doses of the microtubule-stabilizing agent BMS-241027. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience May 2012 - 7137-45 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1529-2401

10.1523/JNEUROSCI.0188-12.2012 doi


Animals
Brain--drug effects
Cognition Disorders--complications
Disease Models, Animal
Dose-Response Relationship, Drug
Doxycycline--pharmacology
Drug Evaluation, Preclinical--methods
Epothilones--pharmacology
Female
Hippocampus--drug effects
Male
Maze Learning--drug effects
Mice
Mice, Inbred C57BL
Mice, Transgenic
Microtubules--drug effects
Nerve Degeneration--drug therapy
Tauopathies--complications
Tubulin Modulators--pharmacology
tau Proteins--antagonists & inhibitors