Rodriguez Camargo, Diana C

The FKBP-rapamycin binding domain of human TOR undergoes strong conformational changes in the presence of membrane mimetics with and without the regulator phosphatidic acid. [electronic resource] - Biochemistry Jun 2012 - 4909-21 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4995

10.1021/bi3002133 doi


Cell Membrane--chemistry
Humans
Liposomes--pharmacology
Micelles
Models, Molecular
Phosphatidic Acids--pharmacology
Protein Structure, Secondary--drug effects
Protein Structure, Tertiary--drug effects
Sirolimus--metabolism
TOR Serine-Threonine Kinases--chemistry
Tacrolimus Binding Protein 1A--metabolism