TY - GEN AU - Koshy,T I AU - Luntz,T L AU - Schejter,A AU - Margoliash,E TI - Changing the invariant proline-30 of rat and Drosophila melanogaster cytochromes c to alanine or valine destabilizes the heme crevice more than the overall conformation SN - 0027-8424 PY - 1991///0110 KW - Alanine KW - Animals KW - Binding Sites KW - Cloning, Molecular KW - Cytochrome c Group KW - chemistry KW - Drosophila melanogaster KW - Heme KW - Hot Temperature KW - Proline KW - Protein Conformation KW - drug effects KW - Rats KW - Recombinant Proteins KW - Spectrum Analysis KW - Structure-Activity Relationship KW - Urea KW - pharmacology KW - Valine N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1073/pnas.87.22.8697 ER -