TY - GEN AU - Thameem,Farook AU - Puppala,Sobha AU - Schneider,Jennifer AU - Bhandari,Basant AU - Arya,Rector AU - Arar,Nedal H AU - Vasylyeva,Tetyana L AU - Farook,Vidya S AU - Fowler,Sharon AU - Almasy,Laura AU - Blangero,John AU - Duggirala,Ravindranath AU - Abboud,Hanna E TI - The Gly(972)Arg variant of human IRS1 gene is associated with variation in glomerular filtration rate likely through impaired insulin receptor signaling SN - 1939-327X PY - 2012///1105 KW - Adult KW - Diabetes Mellitus, Type 2 KW - genetics KW - Female KW - Genotype KW - Glomerular Filtration Rate KW - Humans KW - Insulin KW - Insulin Receptor Substrate Proteins KW - Linkage Disequilibrium KW - Male KW - Mexican Americans KW - Middle Aged KW - Phenotype KW - Polymorphism, Single Nucleotide KW - Proto-Oncogene Proteins c-akt KW - metabolism KW - Receptor, Insulin KW - Signal Transduction N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.2337/db11-1078 ER -