TY - GEN AU - Tong,Gary AU - Wang,Jun-Sheng AU - Sverdlov,Oleksandr AU - Huang,Shu-Pang AU - Slemmon,Randy AU - Croop,Robert AU - Castaneda,Lorna AU - Gu,Huidong AU - Wong,Oi AU - Li,Hewei AU - Berman,Robert M AU - Smith,Christina AU - Albright,Charles F AU - Dockens,Randy TI - A contrast in safety, pharmacokinetics and pharmacodynamics across age groups after a single 50 mg oral dose of the γ-secretase inhibitor avagacestat SN - 1365-2125 PY - 2013///0805 KW - Administration, Oral KW - Adult KW - Aged KW - Aged, 80 and over KW - Alzheimer Disease KW - drug therapy KW - Amyloid Precursor Protein Secretases KW - antagonists & inhibitors KW - Double-Blind Method KW - Female KW - Humans KW - Male KW - Middle Aged KW - Oxadiazoles KW - adverse effects KW - Sulfonamides N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1111/j.1365-2125.2012.04339.x ER -