TY - GEN AU - Li,Yiquan AU - Shao,Jin AU - Shen,Ke AU - Xu,Yufang AU - Liu,Jianwen AU - Qian,Xuhong TI - E2F1-dependent pathways are involved in amonafide analogue 7-d-induced DNA damage, G2/M arrest, and apoptosis in p53-deficient K562 cells SN - 1097-4644 PY - 2013///0107 KW - Adenine KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - Apoptotic Protease-Activating Factor 1 KW - genetics KW - Ataxia Telangiectasia Mutated Proteins KW - Blotting, Western KW - Caffeine KW - Cell Cycle Proteins KW - antagonists & inhibitors KW - Comet Assay KW - Cyclin-Dependent Kinase Inhibitor p21 KW - DNA Breaks, Double-Stranded KW - Dose-Response Relationship, Drug KW - E2F1 Transcription Factor KW - Flow Cytometry KW - G2 Phase Cell Cycle Checkpoints KW - Gene Knockout Techniques KW - methods KW - HCT116 Cells KW - HeLa Cells KW - Hep G2 Cells KW - Humans KW - Inhibitory Concentration 50 KW - K562 Cells KW - M Phase Cell Cycle Checkpoints KW - MCF-7 Cells KW - Naphthalimides KW - Organophosphonates KW - Protein Serine-Threonine Kinases KW - Rats KW - Signal Transduction KW - Time Factors KW - Tumor Suppressor Protein p53 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/jcb.24194 ER -