Li, Yiquan <br/><br/>
E2F1-dependent pathways are involved in amonafide analogue 7-d-induced DNA damage, G2/M arrest, and apoptosis in p53-deficient K562 cells.  [electronic resource] 

 -  Journal of cellular biochemistry  Oct 2012 
 - 3165-77 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1097-4644 
<br/><br/><label>Standard No.: </label>10.1002/jcb.24194  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenine<br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Apoptosis<br/>Apoptotic Protease-Activating Factor 1--genetics<br/>Ataxia Telangiectasia Mutated Proteins<br/>Blotting, Western<br/>Caffeine--pharmacology<br/>Cell Cycle Proteins--antagonists & inhibitors<br/>Comet Assay<br/>Cyclin-Dependent Kinase Inhibitor p21--genetics<br/>DNA Breaks, Double-Stranded<br/>Dose-Response Relationship, Drug<br/>E2F1 Transcription Factor--genetics<br/>Flow Cytometry<br/>G2 Phase Cell Cycle Checkpoints<br/>Gene Knockout Techniques--methods<br/>HCT116 Cells<br/>HeLa Cells<br/>Hep G2 Cells<br/>Humans<br/>Inhibitory Concentration 50<br/>K562 Cells<br/>M Phase Cell Cycle Checkpoints<br/>MCF-7 Cells<br/>Naphthalimides--pharmacology<br/>Organophosphonates<br/>Protein Serine-Threonine Kinases--antagonists & inhibitors<br/>Rats<br/>Signal Transduction<br/>Time Factors<br/>Tumor Suppressor Protein p53--genetics